Can arthritis pain medications be harmful?

Date Updated: 08/05/2020

Answer Section

Many people think that over-the-counter pain relievers must be harmless because they are available without a prescription. But repeated use of these drugs can damage your stomach, kidneys, liver or heart.

Over-the-counter drugs such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve) can cause stomach bleeding and kidney damage and may increase your risk of heart attack and stroke, even early in treatment. Acetaminophen (Tylenol, others) can damage the liver, particularly at dosages higher than recommended.

These drugs are also often ingredients in other prescription and over-the-counter drugs. It's important to read labels or talk to your pharmacist or doctor so that you don't take more than the maximum daily dosage if you're taking more than one medication.

Keep in mind that medication isn't the only treatment for arthritis pain. Mild to moderate arthritis pain may be relieved with a combination of self-care measures and lifestyle changes, such as weight loss, exercise, heat or cold therapy, and physical therapy. Many doctors recommend trying this combined approach before starting medication.

If you need medication to help manage your arthritis pain, use the lowest dose necessary for the shortest time possible. Also, discuss with your doctor which pain medication is most appropriate for your specific situation. All medications — prescription and nonprescription — have risks and potential side effects.